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In a analyze of adjunctive therapy for complicated partial seizures during which individuals had been receiving either carbamazepine or phenytoin in addition to valproate, no adjustment of carbamazepine or phenytoin dosage was needed [see Scientific Experiments].Fertility reports in rats have proven no impact on fertility at oral doses of valproate

fourteen.2 Epilepsy The efficacy of valproate in lowering the incidence of complicated partial seizures (CPS) that happen in isolation or in Affiliation with other seizure styles was recognized in two controlled trials. In a single, multi-clinic, placebo managed research utilizing an insert-on style and design (adjunctive therapy), one hundred fort